Comment 1

P-values or significance level is commonly used (e.g. clinical trials) to determine whether hypothesis tested (comparison of groups’ characteristics) was significant or not. Often outcomes are labeled with “statistically significant” “non-statistically significant” “unlikely due to chance”, or “due to chance”, and so forth. Researchers make conclusions whether to reject the null hypothesis and accept the alternative hypothesis, vice versa, based on significant level.

Alpha levels are set depending on nature of experiments. Researchers set rate how much error is tolerable. For instance, 0.01 alpha level is more liberal than a conservative 0.001 alpha level. Many clinical trials choose alpha level of 0.05. Those drugs on clinical trial with higher alpha level of 0.05 rarely receive FDA approval. In a Phase II clinical trial, where effectiveness and safety is still being evaluated and there are fewer treatment options (for example for rare type diseases), scientist might set a liberal alpha level (Palesch, 2014). Many higher alpha levels are driven by studies’ cost and lower alpha levels by risks such as possible lifelong disability or death. For instance, in Phase III clinical trial such as testing efficacy of hyperbaric oxygen therapy (HBO) on post stroke patients require a conservative alpha level such as 0.02 (Rusyniak, et al. 2018,) or even more stringent level.

Comment 2

The Greek letter alpha is significant in hypothesis testing.  There is not a universal value of alpha that should be used on all statistical tests. Choosing the alpha level is a judgement call of the researcher and it depends on the situation.  Raising the alpha level poses more risk to type I and type II errors. Raising the alpha level is
usually related to having a small or limited sample size.

An experiment when the alpha level 0.01l might be used is in a study of a medical screen for a disease. An example, testing for cancer.  All possibilities must be considered when the choosing the alpha level, The possibilities that he test may give a false positive report of cancer along with a report of egative when the disease was actually positive but the test did not catch the isease. A false positive will increase the patient’s anxiety leading to other ests and in the end the test was negative. This creates a type 1 error. The patient hat tested negative will not get the treatment that they needed for the isease which can lead to death and this is a type II error.  Increasing the alpha level to 0.1 could result n a lower likelihood of a false negative

ln Madeline Leininger and the Transcultural Nursing theory, I need someone to provide me with:

1. Examples from the literature of how the theory has been used.

2. Describe how the theory will be integrated into practice at your institution (or how it will be used as a foundation, framework, etc.). This is an action plan.

Assignment Instructions  For this assignment, write 3–4 pages in which you examine factors that build team success.  Overview  Perhaps, the best predictor of team success is its clarity of purpose and the team’s commitment to achieving it. To support that purpose, a team needs a process that moves smoothly from vision and mission to goals and tasks in order to achieve the desired outcomes. The foundation of both purpose and process is leadership.  Any form of collaboration is an inherently human process. The culture of an organization can dramatically affect team efficacy and performance. The glue that holds teams together is trust. Three factors can help build trust in collaborative environments: performance and competence, integrity, and concern for the well–being of others.  Preparation  Search the Capella library for scholarly articles on leadership styles and qualities of effective team leaders. These articles may or may not also discuss the importance of trust within collaborative teams.  Requirements  Examine two critical components for interprofessional team success: leadership and trust. Address the following: •Identify at least three leadership behaviors that build trust within a team. •Identify at least three leadership behaviors that undermine trust within a team. •Explain the consequences of a team that does not trust its leader in terms of patient safety. •Describe strategies team members can use to build trust among one another in terms of skill, knowledge, and responsibility. •Describe principles of effective interprofessional team leadership. In other words, what skills and qualities should a good team leader possess? Is there a difference between being a good leader and being an effective leader?  Your completed assignment should be 3–4 pages in length, not including the title page and reference page. Support your statements and opinions with references to and citations from at least 3 scholarly or professional resources. Be sure to follow APA guidelines for format and style. In addition: •Include a title page and reference page. •Use Times New Roman font, 12 point. •Double–space.

I want to write a research proposal for pharmaceutics subject in which i have to change a delivery system of a drug to enhance it pharmcokinetic profile for example increase in the absorption.

It should include 1) introductory information with background that lead logically to your hypothesis and specific aim of the assignment, 2) A specific aim detailing how you will test this hypothesis, including a detailed experimental design plan, 3) results 4) the impact that successful completion of this proposal will have on the field. 5) literature review, 6) atleast 10 or more peer reviewed references, and 7) intensive intext citation.

I would also like to have the pdf of references used.

If possible power point presentation of this paper.

In this assignment, you will be exploring actual and potential health problems in the childhood years using a functional health assessment and Erickson’s Stages of Child Development. To complete this assignment, do the following:

1. Using the textbook, complete the “Children’s Functional Health Pattern Assessment.” Follow the instructions in the resource for completing the assignment.
2. Cite and reference any outside sources used in your answers. Include in your assessment a thorough discussion of Erickson’s Stages of Child Development as it pertains to the development age of the child.

While APA format is not required for the body of this assignment, solid academic writing is expected and in-text citations and references should be presented using APA documentation guidelines. This assignment uses a rubric.