1) Minimum 6 full pages (No word count per page)- Follow the 3 x 3 rule: minimum three paragraphs per page

           Part 1: minimum 1 page

           Part 2: minimum 1 page

           Part 3: minimum 4 pages

   Submit 1 document per part

2)¨******APA norms

         All paragraphs must be narrative and cited in the text- each paragraph

         Bulleted responses are not accepted

         Don’t write in the first person 

         Don’t copy and paste the questions.

         Answer the question objectively, do not make introductions to your answers, answer it when you start the paragraph

Submit 1 document per part

3)****************************** It will be verified by Turnitin (Identify the percentage of exact match of writing with any other resource on the internet and academic sources, including universities and data banks) 

********************************It will be verified by SafeAssign (Identify the percentage of similarity of writing with any other resource on the internet and academic sources, including universities and data banks)

4) Minimum 3 references (APA format) per part not older than 5 years  (Journals, books) (No websites)

Part 3:   Minimum 5 references (APA format) per part not older than 5 years  (Journals, books) (No websites) 

All references must be consistent with the topic-purpose-focus of the parts. Different references are not allowed.

5) Identify your answer with the numbers, according to the question. Start your answer on the same line, not the next

Example:

Q 1. Nursing is XXXXX

Q 2. Health is XXXX

6) You must name the files according to the part you are answering: 

Example:

Part 1.doc 

Part 2.doc

__________________________________________________________________________________ 

Part 1: Trends and Issues in Health care

1. Discuss the events that have contributed (or will continue to contribute) to the nursing shortage, or that contribute to a shortage in a region or specialty. 

2. Discuss at least one way that the nursing profession is currently working toward a resolution of this problem. 

3. How the nursing shortage has been addressed in your state (Florida), community, or specialty area.

Part 2: Trends and Issues in Health care

1. Explain how health care reform has helped shift the focus from a disease-oriented health care system to one of wellness and prevention. 

2. Discuss ways in which health care will continue this trend and explain the role of nursing in supporting and facilitating this shift.

3. Provide an example of wellness and prevention initiatives your organization or specialty area has in place.

Part 3: Trends and Issues in Health care

Review the IOM report, “The Future of Nursing: Leading Change, Advancing Health,” and “Campaign for Action: State Action Coalition” website. 

Purpose: Discuss the influence the IOM report and state-based action coalitions have had on nursing practice, nursing education, and nursing workforce development, and how they continue to advance the goals for the nursing profession.

1. Describe the work of the Robert Wood Johnson Foundation Committee Initiative that led to the IOM report, “Future of Nursing: Leading Change, Advancing Health.”

2. Outline the four “Key Messages” that structure the IOM Report recommendations. 

3. Explain how these have transformed or influenced nursing practice, nursing education and training, nursing leadership, and nursing workforce development. 

a. Provide examples.

4. Discuss the role of state-based action coalitions.

a.  Explain how these coalitions help advance the goals specified in the IOM report, “Future of Nursing: Leading Change, Advancing Health.”

5. Research the initiatives on which your state’s (Florida)action coalition is working.

a. Summarize two initiatives spearheaded by your state’s action coalition. 

b. Discuss the ways these initiatives advance the nursing profession.

6. Describe barriers to advancement that currently exist in your state and explain how nursing advocates in your state overcome these barriers.(Florida).

 

Hematopoietic:
J.D. is a 37 years old white woman who presents to her gynecologist complaining of a 2-month history of intermenstrual bleeding, menorrhagia, increased urinary frequency, mild incontinence, extreme fatigue, and weakness. Her menstrual period occurs every 28 days and lately there have been 6 days of heavy flow and cramping. She denies abdominal distension, back-ache, and constipation. She has not had her usual energy levels since before her last pregnancy.

Past Medical History (PMH):
Upon reviewing her past medical history, the gynecologist notes that her patient is a G5P5with four pregnancies within four years, the last infant having been delivered vaginally four months ago. All five pregnancies were unremarkable and without delivery complications. All infants were born healthy. Patient history also reveals a 3-year history of osteoarthritis in the left knee, probably the result of sustaining significant trauma to her knee in an MVA when she was 9 years old. When asked what OTC medications she is currently taking for her pain and for how long she has been taking them, she reveals that she started taking ibuprofen, three tablets each day, about 2.5 years ago for her left knee. Due to a slowly progressive increase in pain and a loss of adequate relief with three tablets, she doubled the daily dose of ibuprofen. Upon the recommendation from her nurse practitioner and because long-term ibuprofen use can cause peptic ulcers, she began taking OTC omeprazole on a regular basis to prevent gastrointestinal bleeding. Patient history also reveals a 3-year history of HTN for which she is now being treated with a diuretic and a centrally acting antihypertensive drug. She has had no previous surgeries.

Case Study Questions

1. Name the contributing factors on J.D that might put her at risk to develop iron deficiency anemia.
2. Within the case study, describe the reasons why J.D. might be presenting constipation and or dehydration.
3. Why Vitamin B12 and folic acid are important on the erythropoiesis? What abnormalities their deficiency might cause on the red blood cells?
4. The gynecologist is suspecting that J.D. might be experiencing iron deficiency anemia.
   In order to support the diagnosis, list and describe the clinical symptoms that J.D. might have positive for Iron deficiency anemia.
5. If the patient is diagnosed with iron deficiency anemia, what do you expect to find as signs of this type of anemia? List and describe.
6. Labs results came back for the patient. Hb 10.2 g/dL; Hct 30.8%; Ferritin 9 ng/dL; red blood cells are smaller and paler in color than normal. Research list and describe for appropriate recommendations and treatments for J.D.

 

This assignment consist of two parts.

Part A

1. Access the Konstanz Information Miner tool at the KNIME web site https://www.knime.com/getting-started-guide
2. Review the information about the KNIME Analytics Platform.
3. Answer the following questions:
   1. How could this platform be used to analyze health care data?  
   2. What benefits does this software have in comparison to commercial products that have similar functionality and use?

Part B

1. Access the journal article by Raghupathi, W., Raghupathi, V., (2014) Big data analytics in healthcare: promise and potential. Health Information Science and Systems 2(3), 1-10  
2. Read the article and define the 4 “Vs” of big data analytics in health care and give an example of each.

Combine your findings writing a 5 page  using APA format. The title page and reference page is not included in the page count.

  

Question 1

A researcher designs a study as a quantitative descriptive study.  Which of the following would NOT typically be part of the research methodology for the study?

Describing a causal effect between the variables.

Using valid and reliable instruments.

Clear conceptual definition of study variables.

Finding a representative sample.

Question 2

Which of the following study designs focuses on finding a cause and effect relationship among variables, but uses a lower level of control?

experimental

descriptive

quasi-experimental

phenomenology

Question 3

A nurse researcher wants to design a study that looks at the relationship between two variables.  She is considering an experimental research design.

True

False

Question 4

A questionnaire has an ID number in one corner that allows the research team to identify the subject. This is an example of:

informed consent.

confidentiality.

  

Discussion Forums

• Discussion forums are a way for you to engage with each other about the course content. Questions will be asked in the forum. Given the time constraints with this course, there are no lectures associated with this class. The course will rely heavily on the discussions. 

• Please make sure that you answer all the discussion board questions and that you periodically review your initial posting for potential questions posed by either me or your classmates. You will receive a weekly grade based on your participation. In order to earn full credit for each discussion, you will need to post a thoughtful, well-written response to the question and respond to your classmates’ responses. You are required to incorporate a minimum 3 intext citations in your initial post and in your subsequent responses. 

• The discussion board replaces the face-to-face interactions and is meant to be a dialogue and a learning activity for the entire class.

• Responses should be at minimum a paragraph, which consists of 5 fully formed sentences. You are required to incorporate a minimum of 3 intext citations in your initial post and in your subsequent responses. A minimum total of 9 intext citations is required for each discussion.

• Responses that are not thoughtful and do not answer the question thoroughly will not receive full credit.

• The content of your postings must demonstrate an understanding of the relevant text material and include citations (3-9 minimum) from either the course reading or supplemental material.

• Please be very cognizant of spelling, grammar, and punctuation, as you will lose points for errors. No cyber speak, please. Use correct grammar, English, and punctuation.

• Only respond to questions that are posted in the discussion forum.

Assignment 3 C (N–Z)

For students with first names starting with the letters N to Z.

Assignments are graded out of a total of 60 points, and they are worth 9% of your total mark.

Submit this assignment after you have completed Unit 3 of the course.

Before you submit this assignment help, make sure you have read the section on Assignments in your Course Orientation.

Part A: Short-answer questions

1. Describe some of the main processes of cancer. (4)

2. Mitosis almost always results in two identical daughter cells. However, in which cells could one find an exception to that rule? (1)

3. What is cytokinesis? (1)

4. Use the following illustration, which shows some stages of three different processes represented by the three columns from left to right, to answer the questions below. (4)

4a. In which columns would you expect genetic recombination? (1)

4b. Crossing-over is not shown in this diagram. Which stage in the diagram is closest to the phase where crossing-over occurs? (E.g., “second column, third stage”) (1)

4c. Indicate all stages in the illustration where the nuclear phase (ploidy) has changed. (2)

5. Compare the final stage of conjugation between an F+ cell and an F- cell with the final stage of conjugation between an Hfr cell and an F- cell. Describe both the donor and the recipient cell and use appropriate terms. (5)

6. What are the two main differences between recombination in meiosis and recombination through mobile elements? (2)

7. Use the following scenario to answer the questions below. (10)

Calico cats have orange and black colour patterns that are determined by two genes, O (on the X chromosome) and B (autosomal). A female calico cat mates with a male cat of the genotype OBb.

7a. What is the phenotype of the father?

7b. Draw one of the possible Punnett squares for this cross.

7c. What is the likelihood that the first kitten has the Calico pattern?

About 50% of the cat’s litter have the same phenotype.

7d. Based on your Punnett square, what is that phenotype and what are the possible genotypes that result in that phenotype?

8. A mother with normal sight has a red-green colour-blind son and a red-green colour-blind daughter. What is the genotype of the father and the mother? What is the phenotype of the father? (3)

9. Use the following scenario to answer the questions below. (10)

In your experiments with Drosophila, you found that the wildtype allele that codes for grey adult insects is sometimes mutated, with mutants having a black colour. Similarly, you find that your population has alleles that code for vestigial wings instead of the wildtype normal wings. (Both mutations are recessive.) You want to know whether the two genes for body colour and wings are linked. In your preliminary crosses you have established a large number of individuals that you require for testcrosses.

9a. Which two genotypes will you use for the testcross? (Hint: One of the two genotypes should be a heterozygous dihybrid.) Use the common wildtype notation (e.g., “ar+ tg”) rather than the allele notation (VvZZ). For simplification, disregard the gender. (2)

9b. Indicate the two phenotypes of your testcross. (1) https://anyessayhelp.com/assignment-help-service/get-business-assignment-help-from-expert-writers/ 

9c. Indicate the genotypes of the progeny (next generation) of the testcross by drawing a Punnett square. (3)

Assuming a total number of 4400 flies for the progeny generation, what are your expectations for the ratio of genotypes if 

9d. the two genes are linked? (1)

9e. the two genes are not linked? (1)

9f. Finally, if the two genes are not linked according to your results, would you expect that they lie on different chromosomes? Explain your answer. (2)

Part B: Multiple-choice questions this homework help

Choose one answer only. Enter your choice into the form field below the question.

Use the following diagram to answer questions 1–3. This diagram shows the incidences of a genetic disease for three generations. We assume that no new mutations occurred in the three generations shown on the diagram.

1. The genetic disease shown here is most likely 

a. autosomal dominant

b. X-linked recessive

c. Y-linked recessive

d. X-linked dominant

e. either a or c

2. Which of the following pairs must be both carriers of the disease?

a. 1 and 5

b. 4 and 7

c. 13 and 16

d. 15 and 19

e. 7 and 9

3. Which of the following groups of three individuals may not be carriers of the disease?

a. 7, 15 and 19

b. 4, 15 and 19

c. 2, 6 and 16

d. 7, 15 and 16

e. 7, 10 and 19

The following diagram shows the result of inbreeding in British aristocracy involving the 

X-linked recessive hemophilia allele. Squares indicate males, circles indicate females, and affected individuals are black. Four generations are included. Note that not all members of a generation are in the same row (e.g., both Beatrice and Leopold belong to the second generation).

4. Carisbrooke is not affected by the disease because 

a. none of his grandparents was a carrier

b. none of his parents was a carrier

c. he is a male

d. he received a copy of the “healthy” allele from his father

e. he received a copy of the “healthy” allele from his mother

5. Which of the following terms can be associated with genomic imprinting?

a. Mutation

b. Maternal inheritance

c. Cytoplasmic inheritance

d. Both b and c

e. Methylation https://smashingessays.com/ 

6. During one cell cycle, the amount of DNA in a cell 

a. remains constant

b. changes once

c. changes twice

d. changes four times

e. changes at every phase of the cycle

7. Mapping of chromosomes is mainly based on 

a. the linkage of genes

b. mutations

c. the likelihood of deletions and inversions

d. transposable elements

e. sex linkage

8. Which of the following processes is crucial for genetic recombination?

a. Prophase and metaphase of meiosis

b. Prophase and metaphase of mitosis

c. S-phase

d. G1 phase

e. Both a and b

9. Which of the following terms/processes could be matched with specialized transduction?

a. Polyploidy

b. RNA virus

c. Hfr cells

d. Bacterial host receives only bacterial DNA.

e. Prophage

10. Which of the following statements describes Hfr cells?

a. They carry an F factor plasmid that is transferred to F- cells.

b. They turn an F- recipient into an F+ cell.

c. They may produce genetic recombination in the recipient cell.

d. They may produce genetic recombination in the donor cell.

e. All of the above

11. Trisomy 21 is an example of 

a. polyploidy

b. aneuploidy

c. cytoplasmic inheritance

d. deletion

e. sex-linked genes

12. Individual genes may be lost in which of the following situation(s)?

a. Duplication

b. Translocation

c. Inversion

d. Deletion

e. All of the above

13. In which situation could it be expected that Mendel’s rules do not apply?

a. Independent assortment

b. Dihybrid crosses

c. Monohybrid crosses

d. Multiple alleles

e. Polygenic inheritance

14. A virus particle may in rare cases only contain bacterial DNA. This may lead to 

a. conjugation

b. transformation

c. the lytic cycle

d. generalized transduction

e. Hfr cells

15. Which of the following term(s) is/are related to oncogenes?

a. Cancer

b. Mutation

c. Metastasis

d. Tumours

e. All of the above

16. What are alternative forms of a gene that govern the same feature, such as flower colour, and occupy corresponding positions on homologous chromosomes?

a. Alleles

b. Loci

c. Homozygotes

d. Coupled traits

e. None of the above

17. Most human somatic cells are 

a. polyploid

b. diploid

c. aneuploid

d. tetraploid

e. haploid

18. A Barr body in a mammalian female cell is 

a. an inactivated oocyte

b. a polar body

c. a degenerate nucleus

d. an inactivated X chromosome

e. an inactivated Y chromosome

19. If the two genes are unlinked, an organism with the genotype of AaBb can produce gametes containing 

a. either Aa or Bb

b. AB, Ab, aB, or ab

c. AaBb

d. AB or ab

e. none of the above

20. A chromosome has the genes U, V, W, and X. They have been shown to have the following crossover frequencies: U and V: 2%; U and W: 9%; U and X: 7%; V and W: 7%; V and X: 5%; and W and X: 2%. What is the sequence of the genes on the chromosome?

a. W-X-V-U

b. U-X-V-W

c. X-W-U-V

d. V-U-W-X

e. None of the above

After receiving the marked assignment back, carefully read all comments from the marker and revise accordingly. If you had any of the MCQ incorrect, make sure to understand why you went wrong. Many studies have shown that revising mistakes results in learning improvement and closes gaps in your understanding. Do not hesitate to contact your Academic Expert if any of the comments are unclear.

If your total mark for the assignment is below 75%, contact your Academic Expert for advice on how to improve your study habits.