Pharmacotherapy for Cardiovascular Disorders 2025

Despite the high mortality rates associated with cardiovascular disorders, improved treatment options do exist that can help address those risk factors that afflict the majority of the population today. Photo Credit: Getty Images/Science Photo Library RF As an advanced practice nurse, it is your responsibility to recommend appropriate treatment options for patients with cardiovascular disorders. To ensure the safety and effectiveness of drug therapy, advanced practice nurses must consider aspects that might influence pharmacokinetic and pharmacodynamic processes such as medical history, other drugs currently prescribed, and individual patient factors. Reference: Murphy, S. L., Xu, J., Kochanek, K. D., & Arias, E. (2018). Mortality in the United States, 2017. Retrieved from https://www.cdc.gov/nchs/products/databriefs/db328.htm To Prepare Review the Resources for this module and consider the impact of potential pharmacotherapeutics for cardiovascular disorders introduced in the media piece. Review the case study assigned by your Instructor for this Assignment. Select one the following factors: genetics, gender, ethnicity, age, or behavior factors. Reflect on how the factor you selected might influence the patient’s pharmacokinetic and pharmacodynamic processes. Consider how changes in the pharmacokinetic and pharmacodynamic processes might impact the patient’s recommended drug therapy. Think about how you might improve the patient’s drug therapy plan based on the pharmacokinetic and pharmacodynamic changes. Reflect on whether you would modify the current drug treatment or provide an alternative treatment option for the patient. By Day 7 of Week 2 Write a 2- to 3-page paper that addresses the following: Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned. Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples. Explain how you might improve the patient’s drug therapy plan and explain why you would make these recommended improvements. CASE STUDY 2: Patient HM has a history of atrial fibrillation and a transient ischemic attack (TIA). The patient has been diagnosed with type 2 diabetes, hypertension, hyperlipidemia, and ischemic heart disease. Drugs currently prescribed include the following: • Warfarin 5 mg po daily MWF and 2.5 mg daily T, TH, Sat, Sun • Aspirin 81 mg po daily • Metformin 1000 mg po bid • Glyburide 10 mg po bid • Atenolol 100 mg po daily • Motrin 200 mg 1–3 tablets every 6 hours as needed for pain please pay attention to the my case study above Rosenthal, L. D., & Burchum, J. R. (2018). Lehne’s pharmacotherapeutics for advanced practice providers . St. Louis, MO: Elsevier. Chapter 34, “Review of Hemodynamics” (pp. 335–340) Chapter 35, “Diuretics” (pp. 341–349) Chapter 36, “Drugs Acting on the Renin-Angiotensin-Aldosterone System” (pp. 351–362) Chapter 37, “Calcium Channel Blockers” (pp. 363–369) Chapter 38, “Vasodilators” (pp. 371–373) Chapter 39, “Drugs for Hypertension” (pp. 375–388) Chapter 40, “Drugs for Heart Failure” (pp. 389–402) Chapter 41, “Antidysrhythmic Drugs” (pp. 403–418) Chapter 42, “Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That Help Normalize Cholesterol and Triglyceride Levels” (pp. 419–439) Chapter 43, “Drugs for Angina Pectoris” (pp. 441–450) Chapter 44, “Anticoagulant and Antiplatelet Drugs” (pp. 451–472) 4 references not more than 5years zero plagiarism

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NUR-621 E8 2025

Select an appropriate staffing model for a 30-bed skilled nursing facility or acute inpatient unit. Create a presentation of 10 to 12 slides, including comprehensive speaker notes to recommend your selected model to nursing leadership and the following information: A description of the staffing model chosen for a 30-bed skilled nursing facility or acute inpatient unit A description of the quality metrics and other data that was used to determine the most appropriate staffing model A description of the budgetary implications of implementing the staffing model A plan for continuous monitoring to ensure the effectiveness and efficiency of the chosen staffing model Include three to five peer-reviewed references in your presentation, including the textbook. While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center. This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

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Medication Error 2025

This is just rewrite to avoid plagiarism A medication error is an error (of commission or omission) at any step along the pathway that begins when a clinician prescribes a medication and ends when the patient actually receives the medication (Agency for Health Care Research and Quality, 2019). In a study conducted by Da Silva and Krishnamurthy (2016), they state that preventable medication errors impact more than 7 million patients and cost almost $21 billion annually across all care settings. About 30% of hospitalized patients have at least one discrepancy on discharge medication reconciliation. Medication errors are an underreported burden that adversely affects patients, providers, and the economy. The study involved a 71-year-old female who accidentally received thiothixene (Navane), an antipsychotic, instead of her anti-hypertensive medication amlodipine (Norvasc) for 3 months. She sustained physical and psychological harm including ambulatory dysfunction, tremors, mood swings, and personality changes and had multiple hospital visits within the 3 months. Despite the many opportunities for intervention, multiple health care providers overlooked her symptoms. Admission medication reconciliation (MED REC) revealed that she was taking metoprolol, doxazosin, alprazolam, citalopram, and thiothixene (Navane) 10 mg twice daily. Upon review of her pill bottles, it was found that her outpatient pharmacy accidentally dispensed Navane (an antipsychotic) instead of Norvasc, and she dutifully took this medication for 3 months. The written prescription was deemed legible. A diagnosis of thiothixene-related drug-induced Parkinsonism was made. Thiothixene was discontinued and her clinical status improved. Da Silva and Krishnamurthy (2018) note that important steps to prevent medication error include clear patient instructions with indications for use on every prescription, utilization of EHR medication import (when available) to review outpatient prescription history, and creating a culture within the medical field of error discussion. Possibilities include medication teams who review admission and discharge reconciliations, team rounding with a pharmacist, encouraging postgraduate trainees and faculty to question indications and utility of medications, and distribution of national and institution data regarding errors, and adverse events. Mandatory training should occur for those providers who fail to document and reconcile medications properly. As a nurse practitioner it is important to monitor the patient especially when poor treatment response occurs or unusual symptoms develop, it is imperative that a review of medications and pill bottle review be part of the initial evaluation. I will implement and use multilevel safeguards, starting with error recognition. Medical error was recently described as the third leading cause of death and only by creating a culture of humility, communication, and teamwork can we learn from our mistakes and hope to decrease preventable errors. References Agency for Health Care Research and Quality. (2019). Medication Errors and Adverse Drug Events. Retrieved from https://psnet.ahrq.gov/primers/primer/23/Medication-Errors-and-Adverse-Drug-Events Da Silva, B., Krishnamurthy, M. 92016). The alarming reality of medication error: a patient case and review of Pennsylvania and National data. Retrieved from https://www.tandfonline.com/doi/full/10.3402/jchimp.v6.31758

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assignment 2025

Benchmark – Capstone Change Project Objectives Review your problem or issue and the cultural assessment. Consider how the findings connect to your topic and intervention for your capstone change project. Write a list of three to five objectives for your proposed intervention. Below each objective, provide a one or two sentence rationale. After writing your objectives, provide a rationale for how your proposed project and objectives advocate for autonomy and social justice for individuals and diverse populations. This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion. You are not required to submit this assignment to Turnitin. Benchmark Information This benchmark assignment assesses the following programmatic competencies: RN to BSN 1.5 : Advocate for autonomy and social justice for individuals and diverse populations

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OL 665 Final Project 2025

For this project, you will choose a not-for-profit organization of your choice—it must be a 501(c)(3) organization—and develop a strategic analysis. You will report on key areas of the organization and evaluate each for its effectiveness in ensuring the long-term sustainability of the organization. Use the following question to guide your strategic analysis. I. Introduction II. Analysis III. Evaluation IV. Conclusion All elements must be addressed. Rubric for this assignment is posted as well as milestones one, two and three so assistance on the essay.

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