2023 Assignment Controversy Associated With Dissociative Disorders The DSM 5 is a diagnostic tool It has evolved over

Nursing 2023 Week 9

Assignment Controversy Associated With Dissociative Disorders The DSM 5 is a diagnostic tool It has evolved over 2023 Assignment

Assignment: Controversy Associated With Dissociative Disorders

The DSM-5 is a diagnostic tool. It has evolved over the decades, as have the classifications and criteria within its pages. It is used not just for diagnosis, however, but also for billing, access to services, and legal cases. Not all practitioners are in agreement with the content and structure of the DSM-5, and dissociative disorders are one such area. These disorders can be difficult to distinguish and diagnose. There is also controversy in the field over the legitimacy of certain dissociative disorders, such as dissociative identity disorder, which was formerly called multiple personality disorder.

In this Assignment, you will examine the controversy surrounding dissociative disorders. You will also explore clinical, ethical, and legal considerations pertinent to working with patients with these disorders.

Photo Credit: Getty Images/Wavebreak Media

The Assignment (3-4 pages)
  • Explain the controversy that surrounds dissociative disorders.
  • Explain your professional beliefs about dissociative disorders, supporting your rationale with at least three scholarly references from the literature.
  • Explain strategies for maintaining the therapeutic relationship with a client that may present with a dissociative disorder.
  • Finally, explain ethical and legal considerations related to dissociative disorders that you need to bring to your practice and why they are important.

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2023 Refer to Ch 3 of Fundamentals of Early Childhood Education and the University Library to choose six

Nursing 2023 discussion

Refer to Ch 3 of Fundamentals of Early Childhood Education and the University Library to choose six 2023 Assignment

 

Refer to Ch. 3 of Fundamentals of Early Childhood Education and the University Library to choose six early childhood theorists.
 

Research the Internet for the definition of a matrix.  

Create a matrix of six theorists that briefly describes the following for each theorist: His or her major contributions to the field

The theory for which he or she is known

How his or her work has influenced early childhood today.

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2023 Determine the descriptive statistic that Differentiate descriptive from inferential statistics that answer clinical questions about

Nursing 2023 Identifying And Interpreting Descriptive Statistics

Determine the descriptive statistic that Differentiate descriptive from inferential statistics that answer clinical questions about 2023 Assignment

 Determine the descriptive statistic that 

  • Differentiate descriptive from inferential statistics that answer clinical questions about the evidence.
  • Interpret research results using the four rules of looking at data. 
  • Value the impact that misrepresentation of research results can have on evidence and, in turn, on nursing practice. is reported, and indicate what it means.

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2023 Practice Experience Stakeholder Analysis The next step in the process is to begin identifying the challenges and

Nursing 2023 Practice Experience: Stakeholder Analysis

Practice Experience Stakeholder Analysis The next step in the process is to begin identifying the challenges and 2023 Assignment

 

Practice Experience: Stakeholder Analysis

The next step in the process is to begin identifying the challenges and impediments to implementing a quality improvement plan. In the analysis consider the individuals affected by the change as well as the cost of implementing the quality improvement plan.

Post a description of some of the proposed action steps for implementing improved practice, and explain where potential challenges might compromise your proposed improvement project. Describe what resources are needed for your solution, and explain whether or not those resources are cost-effective. Continue to collaborate with the selected individuals in your practice environment as needed in the development of the Practice Experience Project, and share this information with your group.

Read and respond to two or more of your colleagues’ postings from the Discussion question. Provide feedback on potential challenges you see might compromise the improvement project and what other resources might be more cost effective. As a member of a community of practice, help each other refine and clarify the patient-centered Practice Experience Project.

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2023 This week we will discuss gastrointestinal and hepatobiliary disorders Please take a look at the week

Nursing 2023 Assignment:week 4Pharmacotherapy For Gastrointestinal And Hepatobiliary Disorders,NURS 6521: Advanced Pharmacology

This week we will discuss gastrointestinal and hepatobiliary disorders Please take a look at the week 2023 Assignment

 

This week we will discuss gastrointestinal and hepatobiliary disorders. Please take a look at the week 4 assignment case posted below. A copy of the midterm exam study guide is available in week 5 and week 6 resources.  

Week 4 Assignment

By Day 7 of Week 4:

Write a 1-page paper that addresses the following:

  • Explain your diagnosis for the patient, including your rationale for the diagnosis.
  • Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
  • Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.
  • Please review the rubric.

Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and diarrhea. The patient has a history of drug abuse and possible Hepatitis C. HL is currently taking the following prescription drugs:

  • Synthroid 100 mcg daily
  • Nifedipine 30 mg daily
  • Prednisone 10 mg daily

 

Gastrointestinal (GI) and hepatobiliary disorders affect the structure and function of the GI tract. Many of these disorders often have similar symptoms, such as abdominal pain, cramping, constipation, nausea, bloating, and fatigue. Since multiple disorders can be tied to the same symptoms, it is important for advanced practice nurses to carefully evaluate patients and prescribe a treatment that targets the cause rather than the symptom.  

Once the underlying cause is identified, an appropriate drug therapy plan can be recommended based on medical history and individual patient factors. In this Assignment, you examine a case study of a patient who presents with symptoms of a possible GI/hepatobiliary disorder, and you design an appropriate drug therapy plan.

To Prepare
  • Review the case study assigned by your Instructor for this Assignment
  • Reflect on the patient’s symptoms, medical history, and drugs currently prescribed.
  • Think about a possible diagnosis for the patient. Consider whether the patient has a disorder related to the gastrointestinal and hepatobiliary system or whether the symptoms are the result of a disorder from another system or other factors, such as pregnancy, drugs, or a psychological disorder.
  • Consider an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
By Day 7 of Week 4

Write a 1-page paper that addresses the following:

  • Explain your diagnosis for the patient, including your rationale for the diagnosis.
  • Describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
  • Justify why you would recommend this drug therapy plan for this patient. Be specific and provide examples.

Reminder: The College of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The Sample Paper provided at the Walden Writing Center offers an example of those required elements (available at http://writingcenter.waldenu.edu/57.htm). All papers submitted must use this formatting.

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2023 Rough Draft Quantitative Research Critique and Ethical Considerations Write a critical appraisal that demonstrates comprehension of

Nursing 2023 Rough Draft Qualitative Research Critique and Ethical Considerations

Rough Draft Quantitative Research Critique and Ethical Considerations Write a critical appraisal that demonstrates comprehension of 2023 Assignment

Rough Draft Quantitative Research Critique and Ethical Considerations

Write a critical appraisal that demonstrates comprehension of two quantitative researchough studies. Use the “Research Critique Guidelines – Part II” document to organize your essay. Successful completion of this assignment requires that you provide a rationale, include examples, and reference content from the study in your responses.

Use the practice problem and two quantitative, peer-reviewed research articles you identified in the Topic 1 assignment to complete this assignment.

In a 1,000–1,250 word essay, summarize two quantitative studies, explain the ways in which the findings might be used in nursing practice, and address ethical considerations associated with the conduct of the study.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

AttachmentsNRS-433V-RS3-ResearchCritiqueGuidelinesPart II.docx
RUBRIC

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2023 Julian Fils Julian Fils Week Two Neurotransmitters and Receptor Theory COLLAPSE Discussion Neurotransmitters and Receptor Theory Explain the agonist to antagonist

Nursing 2023 WEEK 2 6630 RESPONSES

Julian Fils Julian Fils Week Two Neurotransmitters and Receptor Theory COLLAPSE Discussion Neurotransmitters and Receptor Theory Explain the agonist to antagonist 2023 Assignment

Julian Fils Julian Fils: (Week Two)Neurotransmitters and Receptor TheoryCOLLAPSE

Discussion: Neurotransmitters and Receptor Theory

Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact psychopharmacologic treatments’ efficacy.

In simple terms, an agonist creates a specific action, and the antagonist opposes a particular activity. Neurotransmitters that occur naturally stimulate receptors and are thus agonists. Some medications also stimulate receptors and are therefore agonists as well. The mechanism of partial agonists or stabilizers the drugs stimulate the receptors lesser than natural neurotransmitter. It is a common misconception that antagonists are the opposite of agonists because they block agonists’ actions. However, although antagonists prevent agonists’ efforts, they have no activity of their own in the agonist’s absence (Stern et al., 2016).

For this reason, antagonists are sometimes called “silent.” Inverse agonists, on the other hand, do have opposite actions compared to agonists. That is, they not only block agonists but can also reduce activity below the baseline level when no agonist is present. Thus, the agonist spectrum reaches from full agonists to partial agonists through “silent” antagonists and finally inverse agonists (Stahl, 2013).

Compare and contrast the actions of g couple proteins and ion gated channels

Neurotransmitters trigger G-protein-linked and ion-channel-linked cascades.  There are four elements linked to the G-protein-linked system. The first element is the neurotransmitter, also referred to as the first messenger. The second is the G-protein coupled receptors which have seven transmembrane regions. The third element a G protein, which is a connecting protein. The fourth element is an enzyme that can synthesize a second messenger when activated (Stahl, 2013).  The first steps involve the neurotransmitter binding to the receptor. It also changes the form of the receptor, which allows it to fit with the G protein. Then, the G protein binding is conformed to the receptor of the neurotransmitter. The two receptors (neurotransmitter and the G protein) work with each other, which then bind to enzyme E and synthesizes the second messenger (Stahl, 2013).

Ion channel receptors are a vital component of nervous system signaling, allowing rapid and direct conversion of a chemical neurotransmitter message to an electrical current. Efficient neurotransmission requires the precise interplay of various neurotransmitter receptors at pre-and post-synaptic compartments. Ligand-gated ion channels play a central role in intercellular communication in the nervous system. Ion channels are the cellular machinery for ion flux across the membrane and, therefore, the basis of the electrical excitation of neurons. Ligand-gated ion channels are oligomeric protein assemblies that convert a chemical signal into an ion flux through the post-synaptic membrane and are involved in essential brain functions such as attention, learning, and memory (Li et al., 2015).

Explain how the role of epigenetics may contribute to pharmacologic action

Epigenetics describes genetic information that is ‘beyond’ or ‘above’ that information coded solely by our genetic code (Stefanska & MacEwan, 2015). Prior research has shown that the initial epigenetic pattern was set during life and gave each neuron its life-long personality. However, recent studies have shown that these neurons are changing. Depending on what happened to them, such as stress, child abuse, dietary deficiencies, psychotherapy, drug abuse, or psychotherapeutic medications, the previously silent genes are now activated once active genes can become silenced. Thus, causing favorable and unfavorable developments. Favorable epigenetics may trigger learning or experience therapeutic effects on medications, and inimical epigenetic mechanisms may trigger drug abuse, addiction, anxiety disorder, or chronic pain (Stahl, 2013). 

Explain how this information may impact the way you prescribe medications to patients. Include a specific example of a situation or case with a patient in which the psychiatric mental health nurse practitioner must be aware of the medication’s action.

As prescribers, psychiatric nurse practitioners must understand the biological and physical aspects of prescribing medication to the mental health population. These medications directly affect the receptors and neurons; therefore, it is imperative to understand the mechanism of action. Recently at work, a geriatric psychiatric patient with a urinary tract infection was having difficulty sleeping. The nurse asked about trazodone as a PRN for sleep. The Psychiatrist explained that trazodone inhibition of the reuptake of serotonin makes it an antidepressant. It is essential to know it also blocks alpha- receptors that can give the side effect of orthostatic hypotension, especially in older patients. What is also crucial is to note that the anticholinergic effects of trazodone cause delirium and confusion.

In this example, a study was conducted by Lockwood & Youssef  (2017), where the study of epigenetic effects on the Brain-Derived Neurotrophic Factor (BDNF)  in patients with bipolar disorder types I and II and major depressive disorder. In this study, methylation was investigated when patients were in various mood states, including manic, hypomanic, mixed, euthymic, and depressed. The effects of valproic acid and lithium and the impact on BDNF were studied. The results have shown that in a mixed or manic state, BDNF methylation levels approximated that of the control subjects. In addition to that, the patients that were in euthymic or depressed states had significantly higher BDNF methylation levels (Lockwood & Youssef, 2017).

References

Li, S., Wong, A. H. C., & Liu, F. (2015). Ligand-gated ion channel interacting proteins and their role in neuroprotection. Frontiers in Cellular Neuroscience, 8. https://doi.org/10.3389/fncel.2014.00125

Lockwood, L., & Youssef, N. (2017). Systematic review of epigenetic effects of pharmacological agents for bipolar disorders. Brain Sciences, 7(12), 154. https://doi.org/10.3390/brainsci7110154

Stahl, S. (2013). Stahl’s essential psychopharmacology print and online bundle: Neuroscientific basis and practical applications. Cambridge University Press.

Stefanska, B., & MacEwan, D. J. (2015). Epigenetics and pharmacology. British Journal of Pharmacology, 172(11), 2701–2704. https://doi.org/10.1111/bph.13136

Stern, T. A., M Fava, Wilens, T. E., & Rosenbaum, J. F. (2016). Massachusetts general hospital psychopharmacology and neurotherapeutics. Elsevier.

Deepinder Bhandohal Week 2 DiscussionCOLLAPSE

Foundational Neuroscience

1.  Explain the agonist-to-antagonist spectrum of action of psychopharmacologic agents, including how partial and inverse agonist functionality may impact the efficacy of psychopharmacologic treatments.

Agonists are agents that activate receptors upon their binding, similar to the effect of neurotransmitters, hormones, and other endogenous regulators. Antagonists on the other hand do not affect the action of the receptor but act by blocking the receptor’s effectiveness to prevent binding of other drugs or endogenous molecules for activation. Therefore, an antagonist is a drug that has a receptor binding affinity but do not initiate any intrinsic activity (Seyedabadi, Ghahremani, & Albert, 2019).

Partial agonists have moderate activity compared to full agonists, often producing half the effect. A partial agonist can thus be an agonist-antagonist as it blocks the binding of other molecules while producing limited activity. An inverse agonist binds to the agonist binding site on the receptor but elicits an opposite pharmacological effect. Therefore, partial and inverse agonists influence the efficacy and outcomes of the treatments.

2.  Compare and contrast the actions of G-coupled proteins and ion gated channels.

G-protein coupled receptors (GPCRs) constitute a large family of receptors on the cellular plasma membranes that utilize a G protein to transmit signals inside the cell. Disorders in G-protein coupled receptors may result in diseases as they serve multiple functions within the body. Different responses are elicited by the G-protein coupled receptors following the interaction of G-protein subunits with other proteins within the cell. The subunits (α subunit, and another made up of the β and γ subunits) are produced from the division of G-protein following the binding with guanosine triphosphate. The interaction of these subunits with other proteins triggers diverse signaling pathways within the cell (Seyedabadi, Ghahremani, & Albert, 2019).

Ion channels are proteins that enable the flow of specific ions into and out of the cell. There are three types of gated ion channels; mechanically-gated ion channels, voltage-gated ion channels, and ligand-gated ion channels. Ligand-gated ion channels are ionotropic receptors that close or open in response to ligand binding. Voltage-gated ion channels open or close in response to changes in the membrane potentials. Membrane proteins activated by a GPCR can interact with ligand-gated ion channels to prompt their opening or closing (Alexander et al., 2019).

3.  Explain how the role of epigenetics may contribute to pharmacologic action.

Epigenetics is gene regulation where the gene expression patterns are changed following reversible modification of DNA, RNA, or proteins. Epigenetic alterations enable the understanding and identification of diseases like neurodegenerative disorders or cancers. DNA methylation is an example of disease-causing alterations. Responses to drugs vary based on the cellular changes caused by epigenetic alterations or genetic heterogeneity (Rosenthal & Burchum, 2018).

4.  Explain how this information may impact the way you prescribe medications to patients. Include a specific example of a situation or case with a patient in which the psychiatric mental health nurse practitioner must be aware of the medication’s action.

Prescribing medications needs to take account of the patient’s characteristics especially the family history and the genetic implications on diagnosis and treatment. McClarty, Fisher, and Dong (2018) point out the effect of age on dementia treatment, especially when using antipsychotics for the psychological, behavioral, and psychosis symptoms. The treatment has various side effects and is often ineffective due to the effects of aging on drug metabolism and clearance. Age-induced epigenetic alterations also result in pharmacodynamic and pharmacokinetic changes that influence the antipsychotic action of the medication (Nguyen et al., 2020). Epigenetic changes also cause an increase in side effects and altered efficacy of antipsychotics due to histone modifications. Awareness of these changes would inform the prescription decision, especially for the antipsychotics to ensure minimal side effects and maximum efficacy of the selected medication (Camprodon & Roffman, 2016).

References

Alexander, S., Mathie, A., Peters, J. A., Veale, E. L., Striessnig, J., Kelly, E., Armstrong, J. F., Faccenda, E., Harding, S. D., Pawson, A. J., Sharman, J. L., Southan, C., Davies, J. A., & CGTP Collaborators (2019). The Concise Guide to Pharmacology 2019/20: Ion channels. British journal of pharmacology176 Suppl 1(Suppl 1), S142–S228. https://doi.org/10.1111/bph.14749

Camprodon, J. A., & Roffman, J. L. (2016). Psychiatric neuroscience: Incorporating pathophysiology into clinical case formulation. In T. A. Stern, M. Favo, T. E. Wilens, & J. F. Rosenbaum. (Eds.), Massachusetts General Hospital psychopharmacology and neurotherapeutics (pp. 1–19). Elsevier. 

Guidelines on prescribing practice in mental health: A systematic review. Psychiatry Research284. https://doi-org.ezp.waldenulibrary.org/10.1016/j.psychres.2019.112671

McClarty, B. M., Fisher, D. W., & Dong, H. (2018). Epigenetic Alterations Impact on Antipsychotic Treatment in Elderly Patients. Current treatment options in psychiatry5(1), 17–29.

Nguyen, T., Seiler, N., Brown, E., & O’Donoghue, B. (2020). The effect of Clinical Practice

Rosenthal, L. D., & Burchum, J. R. (2018). Lehne’s pharmacotherapeutics for advanced practice providers. St. Louis, MO: Elsevier.

Seyedabadi, M., Ghahremani, M. H., & Albert, P. R. (2019). Biased signaling of G protein coupled receptors (GPCRs): Molecular determinants of GPCR/transducer selectivity and therapeutic potential. Pharmacology & therapeutics200, 148–178. https://doi.org/10.1016/j.pharmthera.2019.05.006

2 SOURCES ON EACH DISCUSSION

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2023 Choose one of the congenital disorders discussed in your text book and create a concept

Nursing 2023 Hypospadias

Choose one of the congenital disorders discussed in your text book and create a concept 2023 Assignment

 

Choose one of the congenital disorders discussed in your text book and create a concept map. You can easily create a concept map using the insert tab in Microsoft Word. Click on Shapes, and drag the shape you choose to your paper. Then right click to add text to your shape. You can go to the format tab by right clicking on your shape to add color, depth, and other special effects. Be sure to cite your concept map in APA format.

Be sure to cover these topics:

  1. Pathophysiology
  2. Assessment findings
  3. Diagnostic tests – labs, x-rays etc.
  4. Focused assessment
  5. Medications, surgical procedures and other treatments
  6. Preventative measures, risk factors, or at risk groups
  7. What client teaching might a practical nurse reinforce under the guidance of the RN?
  8. Prognosis and long term outlook for the patient
  9. Support groups
  10. Resources (cited in APA format)

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2023 Post a description of the patient case from your experiences observations and or clinical practice from the last 5

Nursing 2023 Give A Description Of The Patient Case From Your Experiences, Observations, And/or Clinical Practice From The Last 5 Years. Then, Describe Factors That Might Have Influenced Pharmacokinetic And Pharmacodynamic Processes Of The Patient You Identified.

Post a description of the patient case from your experiences observations and or clinical practice from the last 5 2023 Assignment

 Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case. Be specific and provide examples. 

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2023 1 Describe how your attitude of including aspects of health literacy changed during

Nursing 2023 Reflection Essay

1 Describe how your attitude of including aspects of health literacy changed during 2023 Assignment

1. Describe how your attitude of including aspects of health literacy changed during this course.

2. Describe your approach to incorporating evidence-based literature in health teaching.

3. Describe one theory of teaching or learning that you applied it to your power point presentation.

4. Describe two ways that you have grown as a health educator by taking health promotion course

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