Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion, whereas pharmacodynamics describes what the drug does to the body.

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When selecting drugs and determining dosages for patients, it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.

For this Discussion, you reflect on a case from your past clinical experiences and consider how a patient’s pharmacokinetic and pharmacodynamic processes may alter his or her response to a drug.

To Prepare

• Review the Resources for this module and consider the principles of pharmacokinetics and pharmacodynamics.
• Reflect on your experiences, observations, and/or clinical practices from the last 5 years and think about how pharmacokinetic and pharmacodynamic factors altered his or her anticipated response to a drug.
• Consider factors that might have influenced the patient’s pharmacokinetic and pharmacodynamic processes, such as genetics (including pharmacogenetics), gender, ethnicity, age, behavior, and/or possible pathophysiological changes due to disease.
• Think about a personalized plan of care based on these influencing factors and patient history in your case study.

By Day 3 of Week 1

Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years. Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified. Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case. Be specific and provide examples.

Four  references not more than 5years

Rosenthal, L. D., & Burchum, J. R. (2018). Lehne’s pharmacotherapeutics for advanced practice providers. St. Louis, MO: Elsevier.

• Chapter 1, “Prescriptive Authority” (pp. 1–3)
• Chapter 2, “Rational Drug Selection and Prescription Writing” (pp. 5–9)
• Chapter 3, “Promoting Positive Outcomes of Drug Therapy” (pp. 11–16)
• Chapter 4, “Pharmacokinetics, Pharmacodynamics, and Drug Interactions” (pp. 17–40)
• Chapter 5, “Adverse Drug Reactions and Medical Errors” (pp. 41–49)
• Chapter 6, “Individual Variation in Drug Response” (pp. 51–56)

Clearly, diagnosis is a critical aspect of healthcare. However, the ultimate purpose of a diagnosis is the development and application of a series of treatments or protocols. Isolated recognition of a health issue does little to resolve it.

In this module’s Discussion, you applied the Clark Healthy Workplace Inventory to diagnose potential problems with the civility of your organization. In this Portfolio Assignment, you will continue to analyze the results and apply published research to the development of a proposed treatment for any issues uncovered by the assessment.

To Prepare:

• Review the Resources and examine the Clark Healthy Workplace Inventory, found on page 20 of Clark (2015).
• Review the Work Environment Assessment Template.
• Reflect on the output of your Discussion post regarding your evaluation of workplace civility and the feedback received from colleagues.
• Select and review one or more of the following articles found in the Resources: 
  • Clark, Olender, Cardoni, and Kenski (2011)
  • Clark (2018)
  • Clark (2015)
  • Griffin and Clark (2014)

The Assignment (3-6 pages total):

Part 1: Work Environment Assessment (1-2 pages)

• Review the Work Environment Assessment Template you completed for this Module’s Discussion.
• Describe the results of the Work Environment Assessment you completed on your workplace.
• Identify two things that surprised you about the results and one idea you believed prior to conducting the Assessment that was confirmed. 
• Explain what the results of the Assessment suggest about the health and civility of your workplace.

Part 2: Reviewing the Literature (1-2 pages)

• Briefly describe the theory or concept presented in the article(s) you selected. 
• Explain how the theory or concept presented in the article(s) relates to the results of your Work Environment Assessment.
• Explain how your organization could apply the theory highlighted in your selected article(s) to improve organizational health and/or create stronger work teams. Be specific and provide examples.

Part 3: Evidence-Based Strategies to Create High-Performance Interprofessional Teams (1–2 pages)

• Recommend at least two strategies, supported in the literature, that can be implemented to address any shortcomings revealed in your Work Environment Assessment. 
• Recommend at least two strategies that can be implemented to bolster successful practices revealed in your Work Environment Assessment. 
• 4 references no later than 5years

zero plagiarism

Write a 1,250-1,500 word paper in which you explore decision making methods that can be used to resolve an ethical dilemma using the scenario provided in the assigned reading, “An Unconscious Patient With a DNR Tattoo.” Describe how to use the principles of ethical decision making (reviewed in this topic) to help resolve this ethical dilemma. Address the scenario to generate your conclusions about how you would proceed.

1. What are the dimensions of the ethical dilemma?
2. What are the potential organizational policies to which you will refer?
3. Apply the four core health care ethical principles and the process of ethical decision making in formulating your assistance to the clinical staff.

Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are required to submit this assignment to LopesWrite. Please refer to the directions in the Student Success Center.

This week we will be discussing recent events in health care politics and legislation and their impact on the management of health care organizations. As a health care manager, it will be essential for you to stay up to date on health care politics and policy. 

This is your opportunity to practice finding sources of credible and interesting information! 

Please find a recent (within the past year) news article that discusses health care politics or legislation.  Then, for your original post:

• Provide an overview of your article.
• Explain how the political action or change in legislation discussed in your article might impact the health care industry.  Be sure to describe what types of organization(s) or what group(s) of stakeholders might be impacted.
• Explain how your role as a health care manager might be impacted by the changes discussed above.  Be sure to incorporate course concepts discussed earlier in the term.

Requirement: One original post and two reply posts. 250 word count, apa format, intext citations, please include references

Deadline: Saturday at 11:59 pm.

Instructions

Delta Pacific Case Study

As the change leader for Delta Pacific Company (DPC), you know you need to determine potential organizational  barriers to change for the company’s goal of changing the culture from the more  traditional manufacturing environment to one of a contemporary consulting  environment. Now it’s time to create your strategy to combat barriers to change:

• Assess the potential barriers to changing an organizational culture
• Analyze change strategies appropriate for this type of change
• Determine potential employee resistance behaviors
• Determine the best way to influence employees in the right direction

Since you are the change leader, it  is your responsibility to consider that there will be organizational and human barriers to change. As part of your role, you should take proactive measures and design a change strategy to address potential barriers and resistance.

Conduct academic research and create a plan to present to the CEO and board in which you complete the following change strategy for barriers and resistance:

• Explanation of potential organizational barriers that are most likely to occur for this type of change.
• Description of the employee resistance behaviors.
• Explanation of your strategy to overcome the barriers and resistance.
• Discussion of your strategy recommendations to  overcome barriers and influence employees in the right direction.
• Remember that this is a proposal. Make sure to format your paper properly for your proposal. A proposal is a persuasive  document, so make sure to use proper language and tone. Remember, you are the change leader, and you are writing to the CEO. So use a tone in your proposal that is specific to your audience (the CEO). 

Include your APA-formatted  reference page with at least two credible sources.