Tag Archive for: Nursing Assignment Help

2023 Select a medication used for the treatment of chronic hypertension malignant hypertension heart failure

Nursing 2023 medication used for the treatment of chronic hypertension, malignant hypertension, heart failure, or dyslipidemia

Select a medication used for the treatment of chronic hypertension malignant hypertension heart failure 2023 Assignment

 Select a medication used for the treatment of chronic hypertension, malignant hypertension, heart failure, or dyslipidemia. Share the mechanism of action of this medication and hints for monitoring, side effects, and drug interactions, including CAM, of which one should be aware. In addition, share a time when the use of this medication resulted in a positive or negative outcome in a patient for whom you were caring. Include the name of the medication in the subject line so that the medications can be followed. Include references using APA format. 300 words with intext citation 

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2023 Our cells are filled with intracellular and surface cell receptors Berg Clarke 2018 These

Nursing 2023 Neuroscience

Our cells are filled with intracellular and surface cell receptors Berg Clarke 2018 These 2023 Assignment

Our cells are filled with intracellular and surface cell receptors (Berg & Clarke, 2018).  These receptor proteins are delineated by structure and bind to a variety of substances responsible for creating a reaction or lack thereof. When a ligand binds to the appropriate receptor, signal transduction activates the receptor and produces a biological response ( Berg & Clarke, 2018).  Changes in shape or activity after binding allow signal transmission outside the cell or significant changes within the cell, creating an altered chemical when binding to a ligand-gated-ion channel ( Berg & Clarke, 2018). This post will discuss the agonist/ antagonist spectrum of psychopharmacological agents, G-proteins and ion-gated channels, and epigenetics and their relevance to practice. 

Agonists act like ligands, binding to receptors and causing action (Berg & Clarke, 2018).  Ligands or agonists consist of pharmaceuticals, drugs, light, hormones, and nerve impulses. Ligands and agonists jump in and out of receptors, increasing signaling or changes in the cell.  Antagonists block the standard action of ligands, preventing a response from the receptor (Berg & Clarke, 2018).  Competitive antagonists bind to receptors and prevent ligands from attaching to its preferred receptor, inhibiting stimulation, and leaving the receptor unchanged (Berg & Clarke, 2018).  Naloxone is a competitive antagonist to opiate receptors London, 2017).  The naloxone has a stronger affinity for the receptor, making it more desirable.  The medication discontinues the effects of the opiates by taking their place on the receptor. The higher the dose of opiates circulating the more naloxone required. Due to the excess amount of continued competition for receptors, some patients require multiple doses of naloxone before regaining the ability to breath or regain consciousness (London, 2017). 

G-protein coupled receptors (GPCRs) target 30-50% of psychotropic medications (Stahl, 2013).  As the most abundant protein family, GPCR ligands include neurotransmitters such as serotonin, norepinepherine, and dopamine. After  aligand binds to a GPCR, the GPCR undergoes a conformational change (London, 2017).  Alpha subunit exchanges Guanyl nucleotide phosphates, GTP, GPP, and Alpha unit disassociates and regulates target proteins (London, 2017).  Regulation of neurotransmission is imperative in medication management (London, 2017).  The target proteins can then relay signals via a second messenger, and GTP is finally hydrolyzed to GPP (Lambert, 2004). G-protein receptors tend to have a delay in effect due to a requirement for the accumulation of changed cellular function (London, 2017).  

Ion gated channel linked receptors open and close in response to a chemical message changing signal transduction in the synaptic cleft. These ion channels act like pores in the cellular membrane to allow ion passage (Stahl, 2013).  Transmembrane ion channels open and close in response to the binding of a ligand, differentiated by shape.  The binding will cause the channel to open or close, changing the protein conformation of the entire structure (Berg & Clarke, 2018).  When channels open, ions like potassium, sodium, chloride, and calcium can travel through and change the electrical process creating an intracellular electrical response (Berg & Clarke, 2018).  Psychopharmacology relies heavily on these ion channels in medication management.  Ion-channel linked receptors act along an agonist spectrum; medications can produce conformational changes in these receptors to create any state of the agonist spectrum (Stahl, 2013).

The genetic material in the body is referred to as a genome (Stahl, 2013).  Every cell in the body carries the same DNA but only expresses specific genes required for its domain (Stahl, 2013).  For this reason, cells in the dermis only produce cells required to maintain and rejuvenate the dermis.  Epigenetics is the reason why skin cells differ from brain cells or cardiac cells.  Epigenetics is a term used for the external modifications to the DNA affecting the way it is recognized by cells (Stahl, 2013).  There are thee different methods of epigenetics, DNA myelination, histone acetylation, and microRNA (Stahl, 2013).  Genomes are affected by different exposures during development, environmental chemicals, drugs or pharmaceuticals, aging, and diet (Stahl, 2013).  Alterations in genes may result from these exposures and be passed on to offspring causing a change in the epigenome (Stahl, 2013). 

Psychotropic medications target specific molecular sites to increase neurotransmission. After neurotransmitters release from neurons, they are quickly recollected and utilized again for neurotransmission (Stahl, 2013).  The five essential sites of action for psychotropic medications are 12-transmembrane-region transporter, 7-transmembrane-region-G-protein linked, enzymes, 4-transmembrane-region-ligand-gated ion channel, and 6-transmembrane-region-voltage-gated ion channels (Stahl, 2013).

When cellular alterations occur due to brain injury, neurodegeneration, changes in the extracellular matrix, and changes in voltage and ligand-gated ion channels transpire (Iori, 2018).  A variety of molecular changes, regulation of gene expression, and epigenetic modifications take place as well(Iori, 2018).  As a result, functional impairments such as epilepsy, developmental delay, cognitive/sensory-motor deficits, and drug refractoriness may occur (Iori, 2018).  Many factors affect the outcomes of medication.  Through assessment is required to determine environmental issues, incidents of trauma, and relevant health history. Understanding that many factors influence the effectiveness of the psychotropic medication is imperative when determining the appropriate treatment course (Lambert, 2004).  

Recreational drug use, in combination with prescription medication, is critical to determine.  Like antidepressants, drugs like methylphenidate and cocaine target monoamine transporters; this increases the risk for an oversaturation of serotonin, norepinephrine, or dopamine in the synaptic cleft.  Oversaturation can potentially cause an issue for signal transduction in other neurotransmitters (Stahl, 2013).  This oversaturation of serotonin may cause a toxic level of serotonin, referred to as serotonin syndrome.  Patients with serotonin syndrome/toxicity present with neuromuscular, autonomic, and mental status changes.  Stopping drugs that target monoamine transporters will help decrease levels of serotonin and should return the individual to their normal state of health (Foong, Grindrod, Patel, & Kellar, 2018). 

In conclusion, neurotransmission is the cornerstone of psychopharmacology.  Although enormously complicated, it is imperative providers understand that small changes in cellular function, additional drugs present in the body, and electrolyte imbalances affect prescription medication functions and desired effects.  With a shortage of psychiatric prescribers and a mental health crisis around the world, all healthcare providers must have a proper understanding of psychopharmacology and interactions with other body systems.

References

Berg, K. A., & Clarke, W. P. (2018). Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity. The international journal of neuropsychopharmacology21(10), 962–977. https://doi.org/10.1093/ijnp/pyy071

Foong, A. L., Grindrod, K. A., Patel, T., & Kellar, J. (2018). Demystifying serotonin syndrome (or serotonin toxicity). Canadian family physician Medecin de famille canadien64(10), 720–727.

Iori, V. (2018). Epigenetic and pharmacological targeting of neuroinflammation as novel therapeutic interventions for epilepsy. Retrieved from
https://hdl.handle.net/11245.1/98bfe10f-44d2-4f42-bc1b-2f3e605c3ece

Lambert, D. G. (2004). Drugs and receptors, Continuing Education in Anaesthesia Critical Care & Pain, 4(6), 181–184, https://doi.org/10.1093/bjaceaccp/mkh049

London, E. D. (2017). Imaging drug action in the brain. Place of publication not identified: Routledge.

Stahl, S. M. (2013). Stahl’s essential psychopharmacology: Neuroscientific basis and practical applications (4th ed.). New York, NY: Cambridge University Press 

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2023 Requirements and Guidelines 1 Download the required Milestone 3 Template word document

Nursing 2023 NURSING

Requirements and Guidelines 1 Download the required Milestone 3 Template word document 2023 Assignment

 Requirements and Guidelines

1. Download the required Milestone 3 Template ( word document ).
Nursing Care Issue : Medication errors
2..Milestone 3 is a continuation of and builds upon Milestones 1 and 2. Review the grading criteria and grading rubric for details about requirements including three interventions and evaluation of each.
4.A peer-reviewed scholarly professional nursing journal article (not a website) that is appropriate to the nursing care issue must be obtained from CINAHL via the Chamberlain Online Library and must be available in full text. Use APA format to cite and reference this article. You will write a short summary of this article. ( Word document – article ( peer journal)
Reference of the article : Berdot, S., Roudot, M., Schramm, C., Katsahian, S., Durieux, P., & Sabatier, B. (2016). Interventions to reduce nurses’ medication administration errors in inpatient settings: A systematic review and meta-analysis. International Journal of Nursing Studies, 53, 342-350. doi:10.1016/j.ijnurstu.2015.08.012. Retrived from https://www-sciencedirect-com.chamberlainuniversity.idm.oclc.org/science/article/pii/S002074891500262X#bibl0005

Reference to be used:
Sherwood, G., & Barnsteiner, J. (2012). Quality and Safety in Nursing: A competent Approach to Improving Outcomes. Ams IA: Wiley-Blackwell. –

Berdot, S., Roudot, M., Schramm, C., Katsahian, S., Durieux, P., & Sabatier, B. (2016). Interventions to reduce nurses’ medication administration errors in inpatient settings: A systematic review and meta-analysis. International Journal of Nursing Studies, 53, 342-350. doi:10.1016/j.ijnurstu.2015.08.012. Retrived from https://www-sciencedirect-com.chamberlainuniversity.idm.oclc.org/science/article/pii/S002074891500262X#bibl0005 

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2023 Case Fire the Facilities Manager John Faber is the facilities manager employed at

Nursing 2023 Case Study 2

Case Fire the Facilities Manager John Faber is the facilities manager employed at 2023 Assignment

Case

Fire the Facilities Manager?

John Faber is the facilities manager employed at a 240-bed nursing home for the past 3 years. Before John, the facility had one supervisor over both housekeeping and laundry and a separate maintenance supervisor. Hiring John to supervise all three departments resulted in an annual savings of $7,000 in labor and materials. Prior to joining this facility, John was the maintenance supervisor at a 120-bed skilled care nursing home. Before that, he was a small business owner of a home cleaning service that employed six people. He sold that business 4 years ago. John’s background also includes ownership of a coin laundromat that he disposed of several years ago.

It is time for the annual performance review for all associates. For department heads, the corporate office has authorized a wage increase of between 0% and 6% based on performance. As the administrator (NHA) mulls over John’s performance during the past year, she is pleased with the ongoing cost savings and on-budget performance in facilities services. However, the NHA thinks that she has to hold John accountable for the citation in housekeeping during the certification survey just 2 months ago (rated as E on the Severity/Scope Grid). Last year also the facility had been cited for housekeeping (rated as H on the Severity/Scope Grid), and a resident who had tripped and fallen over a vacuum cleaner cord had sued the facility. Earlier this year, the corporation had settled the claim for $20,000.

The corporate vice president of operations just called and suggested that John should be fired for his poor performance, but the NHA does not share the same view. Her response to the VP of operations was, “I would like to think it over and get back to you tomorrow.” Now, the day has arrived for the NHA to have a phone conference with the VP of operations and a face-to-face meeting with John.

Questions

1.  How should the NHA resolve the conflict with the VP of operations? Provide adequate details, and incorporate in your response the leadership style you suggest using with John.

2.  The NHA’s decision is to not give John a wage increase, which leads to a disagreement between John and the NHA because he regards it as unfair. How should the NHA handle this conflict in which the objective should be to arrive at a win–win solution? Again, provide adequate details.

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2023 Identify a quality improvement opportunity in your organization or practice In a 1 250 1 500 word paper describe the problem or

Nursing 2023 APA style nursing essay from grand canyon university. degree level essay.

Identify a quality improvement opportunity in your organization or practice In a 1 250 1 500 word paper describe the problem or 2023 Assignment

Identify a quality improvement opportunity in your organization or practice. In a 1,250-1,500 word paper, describe the problem or issue and propose a quality improvement initiative based on evidence-based practice. Apply “The Road to Evidence-Based Practice” process, illustrated in Chapter 4 of your textbook, to create your proposal.

Include the following:

  1. Provide an overview of the problem and the setting in which the problem or issue occurs.
  2. Explain why a quality improvement initiative is needed in this area and the expected outcome.
  3. Discuss how the results of previous research demonstrate support for the quality improvement initiative and its projected outcomes. Include a minimum of three peer-reviewed sources published within the last 5 years, not included in the course materials or textbook, that establish evidence in support of the quality improvement proposed.
  4. Discuss steps necessary to implement the quality improvement initiative. Provide evidence and rationale to support your answer.
  5. Explain how the quality improvement initiative will be evaluated to determine whether there was improvement.
  6. Support your explanation by identifying the variables, hypothesis test, and statistical test that you would need to prove that the quality improvement initiative succeeded.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion. 

You are required to submit this assignment to LopesWrite. Refer to the LopesWrite Technical Support articles for assistance.

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2023 Throughout the RN to BSN program students are required to participate in scholarly activities outside of clinical practice or professional practice

Nursing 2023 ASSIGNMENT

Throughout the RN to BSN program students are required to participate in scholarly activities outside of clinical practice or professional practice 2023 Assignment

 

Throughout the RN-to-BSN program, students are required to participate in scholarly activities outside of clinical practice or professional practice. Examples of scholarly activities include attending conferences, seminars, journal club, grand rounds, morbidity and mortality meetings, interdisciplinary committees, quality improvement committees, and any other opportunities available at your site, within your community, or nationally.

You are required to post one scholarly activity while you are in the BSN program, which should be documented by the end of this course. In addition to this submission, you are required to be involved and contribute to interdisciplinary initiatives on a regular basis.

In Topic 10, you will submit a summary report of your scholarly activity. You may use the “Scholarly Activity Summary” resource to help guide this assignment.

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2023 Review the attached PowerPoint presentation Once done answer the following questions 1 Do you think that school nurse should or should

Nursing 2023 Community Nursing – (3) Questions…

Review the attached PowerPoint presentation Once done answer the following questions 1 Do you think that school nurse should or should 2023 Assignment

Review the attached PowerPoint presentation.  Once done answer the following questions: 

1.Do you think that school nurse should or should not be allowed to discuss contraception and pregnancy options with students? What are the possible pros and cons? 

2.Why are some parents choosing not to vaccinate their children in recent years? How do students view this issue? Should this be a parents’ right? Discuss any current events surrounding this issue- research, lawsuits, outbreaks, CDC news.        

3. Do you feel that there are enough programs funding available for children regarding mental health promotion and development issues?  What types of programs are you familiar with?  What areas do you feel are not well addressed.  

-This assignment must be presented in an APA format word document, Arial 12 font. 

-A minimum of 3 evidenced-based references must be used (excluding the class textbook). References must be no older than 5 years.  

-A minimum of 700 words is required.

-No plagiarism!

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2023 Respond to your colleagues posts by sharing your thoughts on their specialty supporting their choice or

Nursing 2023 EBP Response 2

Respond to your colleagues posts by sharing your thoughts on their specialty supporting their choice or 2023 Assignment

 

Respond to your colleagues’ posts by sharing your thoughts on  their specialty, supporting their choice or offering suggestions if  they have yet to choose. 

At least 2 references in each peer responses! 

  

Nursing today is continually changing and expanding.  Staying current on the latest best practices is essential.  Evidence-based practice is a philosophy of implementing the best practices and procedures that have been proven, through research and studies, to facilitate the most favorable outcomes.  In 2010 under the Obama administration and the Affordable Care Act, evidence-based practice (EBP) shifted health care from being based on a reimbursement system and quantity to a system based on evidence and quality (Laureate Education, 2018).  EBP is a long-term problem-solving approach to clinical practice.  These practices integrate evidence from research, clinical experience, theories, expert panels, patient values, and preferences (Melnyk & Fineout-Overholt, 2018).  

For this discussion assignment, I have chosen the Mayo Clinic website.  The Mayo Clinic is the oldest and largest medical group with several multispecialty facilities, combining medical practice with research and education on both a national and international level.  The Clinic has a united model of care that permits multi-disciplinary practice that fosters the team-orientated patient health care and accountability (Bakri & Mayo Clinic, 2014).  Mayo clinic’s mission statement is “To inspire hope and contribute to health and well-being by providing the best care to every patient through integrated clinical practice, education and research” (Mayo Clinic, n. d.).

I believe that the Mayo Clinic is well-grounded in EBP, through the many research activities in which they are involved.  Through research, the Mayo Clinic has been involved in over a hundred medical breakthroughs.  All of these have contributed to the well-being of the patient population.  Good examples are their development of a rapid way to diagnose surgical specimens allowing their surgeons to explore, diagnose, and repair all in one operation.  Also, the mayo clinic isolated thyroxin, the principal hormone of the thyroid gland; only the second time, a pure hormone had been isolated, and the Mayo Clinic developed a DNA test to diagnose anthrax rapidly (Mayo clinic, n. d 

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2023 Module 7 DQ 1 and DQ 2 Tutor MUST have a good command of

Nursing 2023 Discussion Questions Topic 7 DQ 1 and DQ 2

Module 7 DQ 1 and DQ 2 Tutor MUST have a good command of 2023 Assignment

  

Module 7 DQ 1 and DQ 2

Tutor MUST have a good command of the English language

These are two discussion questions

Your DQ1 and DQ2 posts must be at least 150 words and have at least one reference cited for each question. In-text citation, please

Tutor MUST have a good command of the English language

Sources need to be less than five years old and journal/scholarly articles. 

Use only articles that are published between 2015-2018 (except for your theory articles which will be older as you must cite primary sources).

No textbook or direct quotes

Topic 7 DQ 1

Choose one model for EBP implementation. Describe its components and why you believe this model is most appropriate for assisting in translational activities. Contrast this model with another.

Topic 7 DQ 2

Discuss the role of the DNP-prepared nurse in sustaining an EBP culture. What are two effective methods the DNP can use in sustaining an EBP culture?

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2023 Approved Research topic Is telehealthcare a good option for nursing homes THESIS STATEMENT AND SOURCE

Nursing 2023 THESIS STATEMENT AND SOURCE ANALYSIS

Approved Research topic Is telehealthcare a good option for nursing homes THESIS STATEMENT AND SOURCE 2023 Assignment

  

Approved Research topic:  Is telehealthcare a good option for nursing homes?

THESIS STATEMENT AND SOURCE ANALYSIS

For this assignment, you will write the thesis statement for your research paper and provide a preliminary list of at least six sources for approval by your instructor.

  1. Create a single-sentence thesis statement that provides  an overview of your debatable topic as well as the two major arguments  relating to that topic. Keep each of these hints in mind as your craft      your thesis:
  • Your thesis statement should match your approved topic.
  • A thesis statement is a single declarative sentence (not a question).
  • It must be written in the third person only.
  1. Create an APA-formatted reference page with at least six      potential sources that you plan to use both for your annotated      bibliography (due next week) and your final research paper. Keep in mind      the following hints:
  • The appropriate heading for your reference page is the        single word References, which should be centered in lightface Roman font        (not boldface, italics, or underlined.)
  • The reference page should be written using Times New        Roman 12 point font, double-spaced with 1″ margins, and no extra        spaces between citations.
  • Entries should be listed in alphabetical order by        author’s last name.
  • When you cite an author in the reference page, list        the last name first, then the first initial (Lincoln, A.). Do not write        the full first name when using APA formatting.
  • In an APA citation, only the first word and proper        nouns are capitalized in an article or book title. The first word after        a colon is also capitalized (e.g., “The strange quirks of APA:        Understanding capitalization”).
  • For each citation, all lines after the first line of        each entry should be indented one half-inch from the left margin.
  • Refer to this website for great help on exactly how to        properly cite sources and format your reference page: http://owl.english.purdue.edu/owl/resource/560/05/.
  • You will be required to use at least ten scholarly        sources for your final paper, and you may list all ten here for approval        if desired.

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