2023 Gastrointestinal GI and hepatobiliary disorders affect the structure and function of the GI tract

  

Gastrointestinal (GI) and hepatobiliary disorders affect the structure and function of the GI tract. Many of these disorders often have similar symptoms, such as abdominal pain, cramping, constipation, nausea, bloating, and fatigue. Since multiple disorders can be tied to the same symptoms, it is important for advanced practice nurses to carefully evaluate patients and prescribe a treatment that targets the cause rather than the symptom.  

Once the underlying cause is identified, an appropriate drug therapy plan can be recommended based on medical history and individual patient factors. Examine a case study of a patient who presents with symptoms of a possible GI/hepatobiliary disorder, and you design an appropriate drug therapy plan.

Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and diarrhea. The patient has a history of drug abuse and possible Hepatitis C. HL is currently taking the following prescription drugs: 

• Synthroid 100 mcg daily
• Nifedipine 30 mg daily
• Prednisone 10 mg daily

To Prepare

• Review the case study
• Reflect on the patient’s symptoms, medical history, and      drugs currently prescribed.
• Think about a possible diagnosis for the patient.      Consider whether the patient has a disorder related to the      gastrointestinal and hepatobiliary system or whether the symptoms are the      result of a disorder from another system or other factors, such as      pregnancy, drugs, or a psychological disorder.
• Consider an appropriate drug therapy plan based on the      patient’s history, diagnosis, and drugs currently prescribed.

In a 2-page  address the following

• Explain your diagnosis for the patient, including your      rationale for the diagnosis.
• Describe an appropriate drug therapy plan based on the      patient’s history, diagnosis, and drugs currently prescribed.
• Justify why you would recommend this drug therapy plan      for this patient. Be specific and provide examples.

Rosenthal, L. D., & Burchum, J. R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier.

· Chapter 64, “Drugs for Peptic Ulcer Disease” (pp. 589–597)

· Chapter 65, “Laxatives” (pp. 598–604)

· Chapter 66, “Other Gastrointestinal Drugs” (pp. 605–616)

· Chapter 80, “Antiviral Agents I: Drugs for Non-HIV Viral Infections” (pp. 723–743)

Chalasani, N., Younossi, Z., Lavine, J. E., Charlton, M., Cusi, K., Rinella, M., . . . Sanya, A. J. (2018). The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases. Hepatology, 67(1), 328–357. Retrieved from https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.29367

This article details the diagnosis and management of nonalcoholic fatty liver disease. Review this article to gain an understanding of the underlying pathophysiology as well as the suggested pharmacotherapeutics that might be recommended to treat this disorder.