Mr. R is a 48-year-old Hispanic man who has worked the past 10 years as a warehouse worker. He is 5’6”, weighs 175 pounds, and has a waist circumference of 38”. At his last visit at your office, his blood pressure was 140/60 mm Hg. Prior to the visit, he had fasting blood work done, and his primary care provider plans to review the results with him today. The pertinent diagnostic results are as follows: a fasting plasma glucose level of 137 mg/dL, an HDL level of 27 mg/dL, LDL level of 247 mg/dL, a serum triglyceride level of 210 mg/dL. Use the following prompts as guidelines while performing and writing your case study:

1. Identify what this individual is most at risk for based on the information presented in this case above.
2. Explain the significance of this individual’s weight and waist diameter. Explain how this individual is at increased risk for insulin resistance.
3. Explain briefly the differences between hypoinsulinemia, hyperinsulinemia, hyperglycemia, and hypoglycemia as each relate to an individual with type 1 diabetes mellitus and type 2 diabetes mellitus.

For additional details, please refer to the Case Study Guidelines and Rubric document in the Assignments and Rubrics section of the course.

No Plagiarism please, assignment will be checked with Turnitin. 

Will need 4 full pages,  double spaced all throughout the page for the case study, APA Style, Times New Roman, font 12, Title Page and a Reference page. 

Case Study 1:   Structure and Function of the Respiratory System

Brad is 45 years old and has been working as a coal cutter in a mine for the last 25 years. He likes the job because it pays well and the same mine had employed his father. Like many of his colleagues, Brad has had problems with a chronic cough. He has avoided his annual checkups for fear that he will be told he has “black lung,” or coal worker’s pneumoconiosis. The disease causes fibrosis, decreased diffusing capacity, and permanent small airway dilation. In later stages, pulmonary capillaries, alveoli, and airways are destroyed. 

Make sure all of the topics in the case study have been answered.

1.) How can the disease described above create a mismatch between ventilation and perfusion?  Use your understanding of alveolar dead space and physiologic shunt to explain your answer.

2.) Individuals with chronic obstructive pulmonary disease have more difficulty exhaling than inhaling.  Why is this so? 

3.) In general terms, what mechanisms in lung disease can affect diffusing capacity across alveolar membranes?  Use the Fick law to explain your answer.

Cite at least 3 References; journal articles, textbooks, or evidenced-based websites to support the content. 3.

All sources must be within five years (2012-2017).